Nolvadex
tamoxifen
Nolvadex for BodyBuilding (steroid users)
Steroid users take Nolvadex to prevent the effects of estrogen in the body. This
estrogen is most often the result of aromatizing affect of steroids. It
can aid in preventing edema, gynecomastia, and female pattern fat distribution,
all of which might occur when a man’s estrogen levels are too high. Also
these affects can occur when androgen levels are too low, making estrogen
the predominant hormone. This can occur when endogenous androgens have
been suppressed by the prolonged use of exogenous steroids in combination
with cutting of these exogenous sources. Nolvadex works by competitively
binding to target estrogen sites like the breast.
This drug is not toxic nor have any side effects been seen in athletes
who used the drug as an anti-estrogen. This drug is the most popular anti-estrogen
among steroid users by far. Although this drug does not turn out to be
100% effective for everyone, it does seem to exhibit some level of effectiveness
for all. It works so well for some bodybuilders, they can take untraditional
drugs like Dianabol or Anadrol right up to a contest as long as they stack
it with Nolvadex. It would seem wise to take this drug in conjunction
with any steroid cycle. Most reported a dosage of 10mg to 20mg daily got
the job done. Availability of Nolvadex has been fair on the black market.
It is not correct that Nolvadex reduces levels of estrogen: rather, it
blocks estrogen from estrogen receptors and, in those tissues where it
is an antagonist, causes the receptor to do nothing.
However, I would not be surprised if one were to tell a steroid user
that Clomid reduced his gains, he would immediately become afraid that
Clomid reduced his gains (please note that no one I have ever heard of
has noticed this.) Not having been so misled, however, he would not conclude
this from his results. But if an authority publishes that such an effect
occurs, whether it does or not it can become self-fulfilling by biasing
the user.
The fact that Nolvadex will reduce water retention may result in the
user agreeing that gains are less, since weight gain is less, thus reinforcing
the bias. Many bodybuilders take 10-20 mg of Nolvadex each day for the
last month prior to a bodybuilding contest to help reduce water retension
and increase muscle hardness.
Nolvadex for Cancer Treatment
treatment
Tamoxifen
is an antiestrogen (blocks the effect of estrogen on tissue). The precise
mechanism of its action is unknown, but one possible mechanism is that
it binds and blocks estrogen receptors on the surface of cells, preventing
estrogens from binding and activating the cell. It is used in patients
for treating and preventing breast cancer. Controversy currently exists
as to which breast cancer patients will benefit from this treatment.
Tamoxifen or Nolvadex is used for the treatment of invasive breast
cancer, the most common type of breast cancer, following surgery and/or
radiation and for preventing invasive breast cancer in women at high risk
for developing it. Tamoxifen also is used for the treatment of
women following surgery and radiation for a less common type of breast
cancer called ductal carcinoma in situ (DCIS or intraductal carcinoma).
Women who have had ductal carcinoma in situ are at high risk for developing
invasive breast cancer at a later date, and Tamoxifen prevents
development of the invasive cancer in almost half of the women during
the first five years of treatment. Occasionally, Tamoxifen is used
to stimulate ovulation.
Dosing: Tamoxifen should be taken at doses specifically directed
by the physician. Currently, long term dosing is recommended (in excess
of 2 years). Tamoxifen can be taken with food.
Drug Interactions:
Tamoxifen can cause abnormalities of liver
tests and other blood tests, and patients taking it should keep appointments
for blood work to monitor for these side effects. Patients should report
any suspected side effects immediately, especially bleeding and yellowing
of the skin.
Side Effects:
The most common side effects associated with Tamoxifen are: hot
flashes, weight gain, abnormal menstrual periods, and nausea.
